Job Description


Principal Science Manager

£100,000 - £130,000 Per Annum
Job Requirements/Description
Our client are an international company and household name developing and leading the foundational science behind nicotine and other actives. The Principal Science Manager will implement a 5-year strategy focused on human effects based benefit and risk research, which will shape the direction and approach of this novel category for the business. The Principal Science Manager will lead a programme of foundational science, utilising internal and external ecosystem of partnerships, into actives aligned to company strategy, identifying their mechanisms of action, optimum routes of delivery and potential human effects to enable consumer winning product propositions, ideally in a competitive way. The Principal Science Manager will also provide capabilities for assessing the role of non-chemical active means of delivering new stimulating experiences, such as digital, electronic, audio and visual and understanding how this can augment current and future product pipelines. The role will work closely to feed the requirements of the business into the internal preclinical human effects testing team and the scientific human research programme, refine study designs and communicate back out to the business key scientific insights to shape the future pipelines, regulatory strategies and investment choices. Technical leadership of foundational science in the field of human effects. Act as the key link between the New Sciences team and the remainder of the cross functional project teams, translating business requirements and technical insights Evaluate the data generated on actives and products and utilise that data to support any associated regulatory pathways or identify any short, medium or longer-term consumer facing claims In the case of actives other than nicotine, work with product development teams to identify and accelerate compounds or mixtures of compounds that could provide optimised efficacy against one of the three consumer need spaces of relax, sharp and boost In the case of nicotine, work with product development teams to understand the impact of insights gained on human effects and the PRRP pipeline to facilitate consumers switching form cigarettes Build the Intellectual Property and publications necessary to protect competitiveness in this space and contribute to a comms and or regulatory engagement plan Identify partnerships, including ventures, that could accelerate the company strategy, in the area of Scientific Research, and drive the scientific due diligence and scientific agreements associated with themEXPERIENCE Leadership and project management skills, with proven track record of delivering short and long-range science programmes in the field human effects testing Experience in designing and running scientific studies in the fields of chemistry, invitro modelling and human research (clinical or non-clinical) Managed external collaborations with thought leaders, institutes, start-ups and multinationals to strengthen and accelerate the scientific programme Line management; talent and budget (>£1Mn) management Study design and interpretation in a relevant scientific field Proven skills at scientific communication to technical and non-technical, internal and external audiences Collaborative leadership, identification of external collaborations that can strengthen the scientific agenda Education in life Sciences discipline, or in a related field.BENEFICIAL Previous scientific experience in the field of actives beyond nicotine Experience in developing or substantiating products related to the consumer need spaces of relax, sharp and boost. To find out more about Real please visit Real Staffing, a trading division of SThree Partnership LLP is acting as an Employment Agency in relation to this vacancy| Registered office | 1st Floor, 75 King William Street, London, EC4N 7BE, United Kingdom | Partnership Number | OC(phone number removed) England and Wales
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